左雄

发布者:罗昕发布时间:2025-11-19浏览次数:23



 ●个人简介:

姓名:左雄

职称:讲师

学位:博士

籍贯:江西省吉安市永新县

 ●研究方向:不对称有机催化方法学研究、手性药物及天然产物绿色合成研究、生物活性分子的不对称合成及应用研究

 学习经历:

 2020.09 – 2024.06,厦门大学,化学生物学,博士

 2017.09 – 2020.06,贵州大学,制药工程,硕士

 2013.09 – 2017.06,南昌大学,制药工程,学士

 ●工作经历:

 2024.07 – 今,江西师范大学,药学院,讲师

 ●荣誉和获奖:

 无

 ●科研项目:

 (1) 江西省教育厅, 青年项目, GJJ2400201, 33-二取代吲哚骨架及环氧化合物骨架不对称研究, 2024-10 2026-12, 3万元, 在研, 主持

 ●代表性论文:

 (1) Zuo, X.; Wan, Z.; Liao, Z.; Wang, C.; Tan, C.-H.; Huo, S.; Zong, L.* Enantioselectivity and Reactivity Enhancement by 1,1,3,3-Tetramethylguanidine in Bisguanidinium-Catalyzed Asymmetric Alkylation for Construction of Indole Alkaloid Marine Natural Products. ACS Catal. 2023, 13 (24), 15708-15714.

 (2) Liu, X. L.*; Zuo, X.; Wang, J. X.; Chang, S. Q.; Wei, Q. D.; Zhou, Y. A bifunctional pyrazolone-chromone synthon directed organocatalytic double Michael cascade reaction: forging five stereocenters in structurally diverse hexahydroxanthones. Org. Chem. Front. 2019, 6 (9), 1485-1490.

 (3) Zuo, X.; Liu, X.-L.*; Wang, J.-X.; Yao, Y.-M.; Zhou, Y.-Y.; Wei, Q.-D.; Gong, Y.; Zhou, Y. Organocatalytic Reaction of Chromone-Oxindole Synthon: Access to Chromanone-Based Spirocyclohexaneoxindoles with Five Adjacent Stereocenters. J. Org. Chem. 2019, 84 (11), 6679-6688.

 (4) Chang, S.-Q.; Zou, X.; Gong, Y.; He, X.-W.; Liu, X.-L.*; Zhou, Y. Stereocontrolled construction of six vicinal stereogenic centers on a hexahydroxanthone framework through a formal [2+1+3] annulation. Chem. Commun. 2019, 55 (93), 14003-14006.

 (5) Zuo, X.; Chen, S.; Xu, S. W.; Chang, S. Q.; Liu, X. L.*; Zhou, Y.; Yuan, W. C. Highly Efficient, Catalyst-Free, Diastereoselective, Diversity-Oriented Synthesis of Dihydrocoumarin-Pyrrolidine-Spirooxindoles Bearing Three Contiguous Stereocenters. Synthesis 2019, 51 (11), 2339-2350.

 ●联系方式:

邮箱:zuoxiong@jxnu.edu.cn

联系方式:15797682361

办公室:江西师范大学先骕楼3104